The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia

[u/cololz1]

https://www.jci.org/articles/view/171172

[u/Sonnyshut]

I want

[u/Robert_Larsson]

Grünenthal successfully completes Phase I trial with Nociceptin Receptor (NOP) Agonist:

https://www.reddit.com/r/IBSResearch/comments/1v3ybyy/gr%C3%BCnenthal_successfully_completes_phase_i_trial/

More reading:

• Nociceptin receptor Wikipedia
• Spotlight on Nociceptin/Orphanin FQ Receptor in the Treatment of Pain
• Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation
• Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ–NOP Receptor System
• Potential of Nociceptin/Orphanin FQ Peptide Analogs for Drug Development
• Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics

[u/AutoModerator]

Dear commenters,

You may be able to use Sci-Hub, LibGen or /r/scholar to remove barriers to your learning by allowing you to access this research. There is also the Sci-Hub Now extension for your browser.

You can use the "report" feature to remove this comment - just mark it as spam.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.