r/Nootropics • u/Oueqh234 • 1d ago

Discussion Compounds that boost gabaergic tone?

Besides ashwaghanda, SSRIs, l-theanine, bacopa what non-addictive compounds noticeably boost the gabaergic tone?

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u/Forsaken-Net-1092 1d ago

Kava is one I don't see mentioned yet, works on GABA receptors and doesn't build tolerance like benzos do. The taste is absolute garbage but you get used to it after a while

Magnolia bark extract also worth looking into, it potentiates GABA at the receptor site similar to how benzos work but without the addiction risk. I cycle it couple times a week and the effect is more noticeable than l-theanine for me

Lemon balm is another one but it works partly by inhibiting GABA transaminase so you keep more GABA around. Pretty mild though, I use it mostly for sleep stack with magnesium

Taurine is underrated for this honestly, helps GABA synthesis and you can get it cheap anywhere

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u/Louise1467 1d ago

Would it make sense to take magnolia bark and lemon balm together ? Or is there a particular order /frequency that makes most sense?

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u/Johnite123 1d ago edited 1d ago

my personal list : Mangolia bark, skullcap , lemon balm, DHHB, passion flower, gabapentin, kava, apigenin, taurine, fasoracetam.

Other : Valerians, Hops, Gotu, ashwaganda, L theanine, magnesium glycinate, blue lotus, ecklonia cava , Homo taurine , Poppy

Don’t recommend(addicitive) : Phenibut

Night night stack : mangolia bark or DHHB + skullcap + lemon balm

alternate sleep : Passion flower+ apigenin + Lemon balm

work : Gabapentin + fasoracetam

for fun : Kava + lemonbalm + weed

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