r/gabagoodness • u/New_Ebb5963 • 17d ago

Multiple substances Does Pregab make your Gabapentin tolerance higher? NSFW

Just a quick question

15 Upvotes

89% Upvoted

30 comments sorted by

29

u/buttplug50 17d ago

The answer is yes.

4

u/Yaniu 16d ago

What about baclofen

1

u/xMiME_420x Z-drugs 13d ago

I take 450 pregabalin 40 baclofen 2mg clonazapam 70mg Vyvanse 30mg zolpidem

& some other off label things.

Baclofen acts on gaba b . Unlike benzos that act on gaba a

1

u/eknomii 12d ago

Why the baclofen?

2

u/New_Ebb5963 17d ago

Thank you! 🙏🏻

11

u/Book_of_Evil 17d ago

They do the same thing but one is much more bioavailable. Gabapentin has terrible bioavailability

8

u/lowkey_add1ct 17d ago

Yes, they do the same thing basically but pregabalin is much stronger. Lowkey never felt much from gabapentin but pregab always hits

4

u/BlueHDMIV 17d ago

I could never get “high” from gabapentin but Pregabalin blew my mind a few weeks ago. I honestly wasn’t expecting to feel anything at first

0

u/Signal_Muffin2831 14d ago

Lucky you, I only feel drunk and out of it at 150mg so I'll never try to have fun by taking more, unless that's the "secret" to feeling good on this stuff.

3

u/psychonauticlover Pregabalin 17d ago

Y. e. s.

3

u/Powerful_Tap_9859 16d ago

Does anyone know, if you’re trying to taper off gabapentinoids does it make more sense to switch from pregabalin to gabapentin? I’ve been playing with them both for many years, but thinking I need to stop for various reasons and am trying to do a slow taper.

2

u/keepforgettingname6 15d ago

That’s like asking will using Xanax raise your tolerance to Valium? 🙄 ofcourse it will

1

u/Former-Bridge6414 17d ago

Yes, same receptors

1

u/[deleted] 16d ago

[removed] — view removed comment

1

u/skipster88 9d ago

That’s a bit like asking if oxycodone will increase your tolerance for codeine

1

u/Mesosemia 17d ago

Obviously, if you take any pregabalin dose, doesn't matter how much, it will always make the gabapentin seem weaker

6

u/New_Ebb5963 17d ago

It wasnt obvious to me, they're both different substances, didn't know how closely related they were to eachother but knew they worked in the same way, thank you though!

4

u/TheGratitudeBot 17d ago

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3

u/diejesus 17d ago

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2

u/New_Ebb5963 17d ago

For real!