r/Nootropics • • Jan 17 '26

Scientific Study Blocking mobile internet on smartphones improves sustained attention, mental health, and subjective well-being

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59 Upvotes

r/Nootropics • • 1h ago

Seeking Advice Looking for Nootropics that help with Short-Term Memory+Focus as a Machinist with ADHD

• Upvotes

Hey all, I'm looking for suggestions that work well for someone that has to recall numbers and read gauges correctly and quickly. I'm currently on 25mg of Adderall. I'm trying 50-75 mg Bromantane and 30 mg Zinc. There's a noticeable increase in them, but I'm looking for other options. I've also tried Semax intranasally, but I don't think I got the dosage right and I really couldn't tell the difference. I'm stating my career because I've been told that Nootropics work better in situations specific to the effects it gives.


r/Nootropics • • 16h ago

Discussion I’ve been taking anxiety supplements for weeks and feel nothing—how long did it take to actually work for you?

13 Upvotes

For a few weeks now, I've been taking anxiety pills in the hopes that they would help me feel calmer and more in charge. But I don't feel much different so far. I still feel anxious when I wake up and quickly get stressed out. I also act the same way I did before I started them. There hasn't been a precise moment when I thought, This is working.

For some reason, I keep hearing that supplements need time to work. This makes it hard for me to decide whether to keep taking them or stop. How long did it take for you to notice a real, long-lasting change after taking supplements for anxiety? What did you see that they were working for you?


r/Nootropics • • 13h ago

Seeking Advice Measuring small research compounds

2 Upvotes

How do you guys measure mg's (nootropics)? ±8 is very acceptable. Not particularly thrilled to use 500€ for a scale.


r/Nootropics • • 14h ago

Experience I feel like my brain is burning all the time

2 Upvotes

I have phases:

The Nihilist - Nothing seems interesting, low energy, darkest mood.

Obsessed Maniac - I feel pretty productive, mind feels it works fast, too fast. imagination is blasting, but I feel overstimulated by the second half of the day or if left without any work. This phase needs to do something all the time. Brain feels like it's burning.

I prefer being in the maniac phase, but both are unpleasant to be in overall. And no, I'm not bipolar.

I tried using lithium orotate, but it can make me just too flat emotionally.


r/Nootropics • • 5h ago

Seeking Advice FocusX has anyone tried? Advise needed

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0 Upvotes

Bought this recently and wondering if anyone here has actually tried this blend.

It’s 450mg/mL total:

- Alcar 150mg/mL

- Choline chloride 150mg/mL

- L-carnosine 150mg/mL

I’m planning to pin 0.5mL to start, so that would be 75mg of each.

Curious if anyone has firsthand experience with it.

* What dose did you use?

* Did you actually notice anything from it?

* How often were you pinning it?

* Does the ALCAR hurt or burn with this blend?

* Any PIP after?


r/Nootropics • • 16h ago

Discussion Ice bathing as powerful nootropic

0 Upvotes

Hello. I've watched Joe Rogan podcast, where he explains that ice bathing is one of the most powerful nootropicpics. What do you think? It really could be helpful for mental clearance and fight with anxiety. Plus as I understand it is much more effective than simple cold shower.


r/Nootropics • • 1d ago

Seeking Advice Rate my stack for ADHD. Any suggestions?

4 Upvotes

lions mane 500mg, choline 250mg, N acetyl l tyrosine 175mg, bacopa extract 100mg, l theanine 100mg, phosphatidylserine 20% 100mg, astaxanthin 12mg, caffeine usually 100-400mg a day. I also use pramiracetam sometimes for studying. What do u think i could do to edit/improve my stack im trying to maximize focus, energy, productivity as i have adhd. Any suggestions? Also thinking about taking creatine daily as i workout


r/Nootropics • • 1d ago

Discussion Anything I can take to help me STFU?

5 Upvotes

I have a problem with oversharing and regretting it later (worse when drunk). I also have a problem waffling on when talking and filling in the silence. I was wondering if there’s anything I could take to calm my mind and not have the urge to talk. I just want to sit in silence but it seems impossible to do in social situations for me.


r/Nootropics • • 1d ago

Discussion Is Ashwaghanda more harmful than an SSRI?

6 Upvotes

I'm quite anxious and took ssris in the past, which kind of helped but i became more numb and anhedonic on them. SSRIs were a really long time ago and my motivation got better over that time partly because of ADHD meds and a diagnosis.

Because of the numbess i stopped SSRIs and started Ashwaghanda, which helped as well but it made me numb again (i was doing 500mg ksm66 and never tried 250mg). Unliie ssris, Ashwaghanda didn't cause sexual dysfunction.

I'm thinking of switching back to Ashwaghanda but at a lower dose or a low dose SSRIs because anxiety is messing my life up, I'm also irritable because of it.

Which option seems safer/better?


r/Nootropics • • 1d ago

Seeking Advice Would a med more selective to dopamine suit my symptom profile better?

3 Upvotes

So I've been on Wellbutrin for many years, almost five years mainly for my SCT and executive dysfunction and because it used to be so extremely helpful for my mood, apathy, avolition and anhedonia in the past. In the beginning it gave me increased motivation, anticipation and just a great feeling of overall wellbeing all the time. At first it was amazing and worked very well for me.

Unfortunately last year and this year I've noticed it has lost a lot of its effectivness and later on it changed completely and became a killer anxiety provoker instead of a motivation and mood enhancer like it used to be in the past. Particularly this year I've noticed that it has started to give me a lot of strange side effects I never used to have from it before and those seem to related to its noradrenergic effects. And those side effects are frequent thirst, frequent urination, dry mouth, blurry vision that comes and goes, tingling sensations in my head, headaches, dizziness, vertigo, hot flashes, burning sensations, balance issues, insomnia and sleep disturbances, facial twitches, muscle stiffness and weakness etc. And I've also noticed now that it just makes me feel wired, tired, anxious, confused + with a scattered mind, but without any of the mood or motivation benefits it used to give me in the past. Now when I take it, it just makes me anxious, wired and on edge, but with none of the happiness and great feeling of overall wellbeing like it used to give me in the past.

Now I'm wondering if this is just tolerance or is it that my response to it changed over time? Because the anxiety and panic attacks that it gives me nowadays is starting to interfere with my life and it's starting to take a tool on my mental health. I honestly don't think the norepinephrine of this med helps my depression at all. I just think the norepinephrine makes me anxious, wired, tired and confused + with a scattered mind and does no good for me at all. I think it was the weak dopaminergic effects that helped my depression in the first place.

So do you think a med more selective to dopamine would suit my symptom profile better based on everything I've told you now?


r/Nootropics • • 1d ago

Discussion Phenylpiracetam and running?

8 Upvotes

Has anyone tried using phenylpiracetam to enhance running performance? I am running a local fun 10k race in a few days and really want to try and run sub 40min. I have experience using phenylpiracetam in the past for weightlifting and studying (both of which felt effective, particularly weightlifting), but I have never tried using to run. I normally just run after consuming caffeine.


r/Nootropics • • 1d ago

Vendor Report/Q D2D Sales Potential Stack

6 Upvotes

Hey, I’m curious what anyone in d2d sales take? I don’t want anything like addy lol but I’ll take other things. I’m planning on taking brom daily, PPAP and NA-selank pre knocking. Would this be good?. What should I add or remove?


r/Nootropics • • 2d ago

Experience BPC-157 Changed My Response to Vyvanse & Adderall NSFW

87 Upvotes

A weekend ago(9/19), I started BPC-157 for a groin injury (250 mcg 2x/day Sat/Sun). By Sunday, I felt mentally good and functional without my stimulants: much less fatigue/depression, brain fog, anxiety, and none of my usual grogginess (inattentive ADHD & suspected narcolepsy type 2). Unfortunately, I overestimated how long that positive side effect would last.

Since starting BPC-157:

Pro:

  • Noticed I recovered faster from my workouts

Cons:

  • My usual Vyvanse dose (40 mg, Mon–Fri for 5 months) now makes me extremely jittery/overstimulated. Before BPC, Vyvanse greatly reduced anxiety, fatigue & executive dysfunction.
  • I paused Vyvanse for 2 days, thinking. "Oh, BPC-157’s catecholamine system effects might mean I didn’t need stims anymore".
  • Daytime sleepiness returned, turns out, I still need Vyvanse to stay awake & regulate executive functioning.
  • Only 20–25 mg Vyvanse feels tolerable now. A reduction in dosage is great but the anxiety & jitters wasn't
  • Adderall (10 mg, 10 months, only as needed) helped before, but after BPC-157, no executive function benefits, just straight anxiety & overstimulation.

I wish I could continue BPC-157 for my groin strain, but it seems to dampen Vyvanse’s focus/motivation benefits while amplifying its noradrenergic side effects (anxiety, jitteriness, overstimulation, irritablity). I’ve also read reports of BPC-157 causing anhedonia or blunting response to stims, and since I’ve always had some degree of anhedonia/depression from inattentive ADHD, which my stimulants really help me with, I’d rather not risk worsening it. As much as I’d like to be off stimulants, maintaining my mood and motivation towards my career matters more to me. I’ve stopped BPC-157 for now and I’m trying to figure out how long its effects on my dopamine/catecholamine system might last before Vyvanse & adderall work normally again.

Just started selank(250mcg x1/day) and it seems to quiet the overwhelming noradrenergic effects of stims that were amped up by bpc-157 so I'll report its effects later


r/Nootropics • • 1d ago

Seeking Advice Why is AI such a hassle to work with for nootropic/neurology related questions?

1 Upvotes

I find it really challenging to get any meaningful answers/explanations from them I swear I could just ask Claude something as simple as "what are the proven mechanisms and effects of <compound>?" and still get flagged.

Does anybody knows a working prompt format? I don't want AI to just blindly cooperate with me but at least give me some information...


r/Nootropics • • 2d ago

Discussion Is low dose ashwaghanda going to be as blunting?

3 Upvotes

I've tried SSRIs, bacopa, saffron, l-theanine, silexan, phosphatidylserine, ashwaghanda.

Out of all these, only SSRIs and Ashwaghanda work for my anxiety, and l theanine helps a little but that's it. Ashwaghanda unlike SSRIs spares my libido so id rather go back on it than on an SSRI.

However, emotional blunting from ashwaghanda is pretty annoyinyg, i was taking around 500mg ksm66 last time, would 250mg be much less blunting?


r/Nootropics • • 1d ago

Discussion Compounds that boost gabaergic tone?

2 Upvotes

Besides ashwaghanda, SSRIs, l-theanine, bacopa what non-addictive compounds noticeably boost the gabaergic tone?


r/Nootropics • • 1d ago

Seeking Advice First Nootropic Stack Advice?

0 Upvotes

I’m planning on taking bromantane 25mg sublling daily to start, and TAK-653 3-4x weekly at 2.5mg. I may add na-selank. Is this missing anything? Is it stupid lol? Should I get rid of anything?

My goals are to have a lot more energy and motivation to be productive while being able to have laser focus. Focus is my biggest issue.

Brom and TAK is already ordered.


r/Nootropics • • 2d ago

Experience Saffron 30mg experiment let's go!

7 Upvotes

Hi all

From today 30th September 2026, taking 15mg AFFRON SAFFRON EXTRACT capsule, two times a day.

Why?

I get irritated and annoyed very easily. I feel down once or twice a week. I also don't like meeting new people or going to events anymore. I want to improve my general mood, not become more sociable. Feel better inside.

Background

34 years old, male, straight, have a gf, not married, live alone, stable average stress job, emotional, animated, used to be an extrovert/highly sociable until around 2020 (when I reached 28/29). Drink one pint of beer a week. Don't smoke or take drugs.

The bottle has 60 capsules. Let's see how I do after 30days, end of October. Not promoting it, just experimenting.. let's see..


r/Nootropics • • 2d ago

Discussion Should I get semax I’m 18 and riddled with adhd

5 Upvotes

Hey I’m 18 and riddled with adhd and trash at school I can’t focus in anything I do my brain is just fried and thinking about semax but being a pussy is it real and would it help me thanks


r/Nootropics • • 2d ago

Seeking Advice Haven't ordered in a while

10 Upvotes

I haven't ordered in a while (like mid 22 early 2023). I used to use nootropics depot, science.bio and new mind. I was wondering if anyone has replaced these places as trusted vendors. I've looked into it a little but it seemed worth it to ask. I mainly used racetams, phenibut, and would try anything else that sounded interesting while I was looking through.


r/Nootropics • • 2d ago

Seeking Advice Please rate my stack for studying

1 Upvotes

Ppap hcl-30mg
Kw6356-1.5mg
Prl-8-53 - 5mg
Tak 653 - 2mg


r/Nootropics • • 2d ago

Seeking Advice L dopa 100% pure dosage /administration

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7 Upvotes

Hello guys i crossed this product which claims to be pure

L-Dopa (from Mucuna Pruriens extract) 100% pure ,but i did some research and read that its unlike pharma levodopa which has substances to inhibit it conversion out of the brain plus most of Mucuna extracts delivered around 120mg of raw ldopa as this product claims per serving

Guys who are familiar with it whats your experience with it? How do you recommend it should be taken ?

Thanks in advance


r/Nootropics • • 2d ago

Experience Anyone feeling sleepy after Semax?

6 Upvotes

I have adhd. I take 186 mcg SUBQ once a day in the morning.

The effects are great in a way that there are no multiple voices in my head and im able to focus on one thing.

However, I also feel so sleepy. Or maybe because I just had 10 hr sleep.

Anyone has the same experience?


r/Nootropics • • 2d ago

Seeking Advice Thinking of going back to modafinil

3 Upvotes

Looking for current recs on modafinil/armodafinil brands + where people in the US are ordering from these days!!

I’ve had ADHD/focus issues forever and used modafinil and Concerta on and off in the past for deep-work days. I’ve been on bupropion XL 300 mg for about a year. At first it really helped and I felt like I had my drive back, but that effect gradually faded…

So, after a ridiculous amount of appointments trying to get a stimulant prescription, I finally managed to get Vyvanse. Started at 10mg, went up to 20, but it’s basically still doing nothing for me and my psychiatrist also wants weekly appointments. Honestly I’m just over the whole process.

So I’m thinking of going back to modafinil… I see a lot of generic variants (moda, armoda etc). What’s everyone liking these days and where are you guys ordering from?

Also, anyone taking wellbutrin + moda - how’s your experience so far?